RT Book, Section A1 Motzer, Robert J. A1 Feldman, Darren R. A1 Bosl, George J. A2 Jameson, J. Larry SR Print(0) ID 1141274940 T1 Testicular Cancer T2 Harrison's Endocrinology, 4e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259835728 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141274940 RD 2024/03/28 AB Primary germ cell tumors (GCTs) of the testis arising by the malignant transformation of primordial germ cells constitute 95% of all testicular neoplasms. Infrequently, GCTs arise from an extragonadal site, including the mediastinum, retroperitoneum, and, very rarely, the pineal gland. This disease is notable for the young age of the afflicted patients, the totipotent capacity for differentiation of the tumor cells, and its curability; approximately 95% of newly diagnosed patients are cured. Experience in the management of GCTs leads to improved outcome.