RT Book, Section
A1 Ehrmann, David A.
A2 Jameson, J. Larry
SR Print(0)
ID 1141275192
T1 Hirsutism
T2 Harrison's Endocrinology, 4e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259835728
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141275192
RD 2024/04/24
AB Hirsutism,  which  is  defined  as  androgen-dependent  excessive  male-pattern  hair  growth,  affects  approximately  10%  of  women.  Hirsutism  is  most  often  idiopathic  or  the  consequence  of  androgen  excess  associated  with  the  polycystic  ovarian  syndrome  (PCOS).  Less  frequently,  it  may  result  from  adrenal  androgen  overproduction  as  occurs  in  nonclassic  congenital  adrenal  hyperplasia  (CAH)  (Table  17-1).  Rarely,  it  is  a  sign  of  a  serious  underlying  condition.  Cutaneous  manifestations  commonly  associated  with  hirsutism  include  acne  and  male-pattern  balding  (androgenic  alopecia).  Virilization  refers  to  a  condition  in  which  androgen  levels  are  sufficiently  high  to  cause  additional  signs  and  symptoms,  such  as  deepening  of  the  voice,  breast  atrophy,  increased  muscle  bulk,  clitoromegaly,  and  increased  libido;  virilization  is  an  ominous  sign  that  suggests  the  possibility  of  an  ovarian  or  adrenal  neoplasm.