RT Book, Section
A1 Jacobs, Richard F.
A1 Schutze, Gordon E.
A2 Kasper, Dennis L.
A2 Fauci, Anthony S.
SR Print(0)
ID 1141408970
T1 TULAREMIA
T2 Harrison's Infectious Diseases, 3e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259835971
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141408970
RD 2024/04/18
AB Tularemia  is  a  zoonosis  caused  by  Francisella  tularensis.  Humans  of  any  age,  sex,  or  race  are  universally  susceptible  to  this  systemic  infection.  Tularemia  is  primarily  a  disease  of  wild  animals  and  persists  in  contaminated  environments,  ectoparasites,  and  animal  carriers.  Human  infection  is  incidental  and  usually  results  from  interaction  with  biting  or  blood-sucking  insects,  contact  with  wild  or  domestic  animals,  ingestion  of  contaminated  water  or  food,  or  inhalation  of  infective  aerosols.  The  illness  is  characterized  by  various  clinical  syndromes,  the  most  common  of  which  consists  of  an  ulcerative  lesion  at  the  site  of  inoculation,  with  regional  lymphadenopathy  and  lymphadenitis.  Systemic  manifestations,  including  pneumonia,  typhoidal  tularemia,  meningitis,  and  fever  without  localizing  findings,  pose  a  greater  diagnostic  challenge.