RT Book, Section
A1 Walker, David H.
A1 Dumler, J. Stephen
A1 Marrie, Thomas
A2 Kasper, Dennis L.
A2 Fauci, Anthony S.
SR Print(0)
ID 1141410218
T1 RICKETTSIAL DISEASES
T2 Harrison's Infectious Diseases, 3e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259835971
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141410218
RD 2021/05/11
AB The  rickettsiae  are  a  heterogeneous  group  of  small,  obligately  intracellular,  gram-negative  coccobacilli  and  short  bacilli,  most  of  which  are  transmitted  by  a  tick,  mite,  flea,  or  louse  vector.  Except  in  the  case  of  louse-borne  typhus,  humans  are  incidental  hosts.  Among  rickettsiae,  Coxiella  burnetii,  Rickettsia  prowazekii,  and  R.  typhi  have  the  well-documented  ability  to  survive  for  an  extended  period  outside  the  reservoir  or  vector  and  to  be  extremely  infectious:  inhalation  of  a  single  Coxiella  microorganism  can  cause  pneumonia.  High-level  infectivity  and  severe  illness  after  inhalation  make  R.  prowazekii,  R.  rickettsii,  R.  typhi,  R.  conorii,  and  C.  burnetii  bioterrorism  threats.