RT Book, Section A1 Hage, Chadi A. A1 Wheat, L. Joseph A2 Kasper, Dennis L. A2 Fauci, Anthony S. SR Print(0) ID 1141412561 T1 HISTOPLASMOSIS T2 Harrison's Infectious Diseases, 3e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259835971 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141412561 RD 2024/04/25 AB Histoplasma capsulatum, a thermal dimorphic fungus, is the etiologic agent of histoplasmosis. In most endemic areas, H. capsulatum var. capsulatum is the causative agent. In Africa, H. capsulatum var. duboisii also is found; var. duboisii can be differentiated from var. capsulatum as the duboisii yeasts are larger. In Central and South America, histoplasmosis is common and is caused by clades of H. capsulatum var. capsulatum that differ genetically from those involved elsewhere.