RT Book, Section A1 Eaton, Douglas C. A1 Pooler, John P. SR Print(0) ID 1160609699 T1 Clearance and Measures of Renal Function T2 Vander’s Renal Physiology, 9e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781260019377 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1160609699 RD 2024/03/29 AB Define the terms clearance and metabolic clearance rate, and differentiate between general clearance and specific renal clearance.List the information required to calculate clearance.State the criteria that must be met for a substance so that its clearance can be used as a measure of glomerular filtration rate; state which substances are used to measure glomerular filtration rate and effective renal plasma flow.Given data, calculate the clearance of any excreted substance.Predict whether a substance undergoes net reabsorption or net secretion by comparing its clearance with that of inulin or by comparing its rate of filtration with its rate of excretion.Given data, calculate net rate of reabsorption or secretion for any substance.Given data, calculate fractional excretion of any substance.Describe how to estimate glomerular filtration rate from creatinine clearance and describe the limitations of this estimate.Describe how to use plasma concentrations of urea, creatinine, and other endogenously produced substances as indicators of changes in glomerular filtration rate.Describe other clinical measures of renal function.