RT Book, Section A1 Eaton, Douglas C. A1 Pooler, John P. SR Print(0) ID 1160610319 T1 Appendix B T2 Vander’s Renal Physiology, 9e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781260019377 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1160610319 RD 2024/04/20 AB Table Graphic Jump LocationTable B–1.Classes of diureticsView Table||Download (.pdf)Table B–1.Classes of diureticsClassMechanismMajor site affectedCarbonic anhydrase inhibitorsInhibit secretion of hydrogen ions, which reduces reabsorption of bicarbonate and sodiumProximal tubuleLoop diureticsInhibit Na-K-2Cl symporter in luminal membraneThick ascending limb of Henle loopThiazidesInhibit Na-Cl symporter in luminal membraneDistal convoluted tubulePotassium-sparing diureticsInhibit action of aldosteroneCortical collecting tubuleBlock sodium channelsCortical collecting tubule