RT Book, Section A1 Amir, Eitan A2 Harrington, Lea A. A2 Tannock, Ian F. A2 Hill, Richard P. A2 Cescon, David W. SR Print(0) ID 1179326151 T1 Guide to Clinical Studies T2 The Basic Science of Oncology, 6e YR 2021 FD 2021 PB McGraw-Hill Education PP New York, NY SN 9781259862076 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1179326151 RD 2024/04/23 AB To select the optimal treatment for patients, clinical oncologists need to be skilled at critically evaluating data from clinical studies and interpreting these appropriately. Clinicians should also be proficient in the application of diagnostic tests, assessment of risk, and the estimation of prognosis. Equally, scientists involved in translational research should be aware of the problems and pitfalls in undertaking clinical studies. The practice of oncology is increasingly incorporating genomic assessment both to provide information on prognosis and to allow optimal choice of therapy. This chapter provides a critical overview of methods used in clinical research.