RT Book, Section
A1 Kandel, Eric R.
A1 Koester, John D.
A1 Mack, Sarah H.
A1 Siegelbaum, Steven A.
SR Print(0)
ID 1180640398
T1 Propagated Signaling: The Action Potential
T2 Principles of Neural Science, 6e
YR 2021
FD 2021
PB McGraw Hill
PP New York, NY
SN 9781259642234
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1180640398
RD 2024/04/16
AB NERVE  CELLS  ARE  ABLE  TO  CARRY  electrical  signals  over  long  distances  because  the  long-distance  signal,  the  action  potential,  is  continually  regenerated  and  thus  does  not  attenuate  as  it  moves  down  the  axon.  In  Chapter  9,  we  saw  how  an  action  potential  arises  from  sequential  changes  in  the  membrane’s  permeability  to  Na+  and  K+  ions  and  how  the  membrane’s  passive  properties  influence  the  speed  at  which  the  action  potential  is  conducted.  In  this  chapter,  we  describe  in  detail  the  voltage-gated  ion  channels  that  are  critical  for  generating  and  propagating  action  potentials  and  consider  how  these  channels  are  responsible  for  important  features  of  a  neuron’s  electrical  excitability.