RT Book, Section SR Print(0) ID 1101678041 T1 Synaptic Integration in the Central Nervous System T2 Principles of Neural Science, Fifth Edition YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-139011-8 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1101678041 RD 2024/03/29 AB Central Neurons Receive Excitatory and Inhibitory InputsExcitatory and Inhibitory Synapses Have Distinctive UltrastructuresExcitatory Synaptic Transmission Is Mediated by Ionotropic Glutamate Receptor-Channels That Are Permeable to Sodium and PotassiumThe Excitatory Ionotropic Glutamate Receptors Are Encoded by a Distinct Gene FamilyGlutamate Receptors Are Constructed from a Set of ModulesNMDA and AMPA Receptors Are Organized by a Network of Proteins at the Postsynaptic DensityInhibitory Synaptic Action Is Usually Mediated by Ionotropic GABA and Glycine Receptor-Channels That Are Permeable to ChlorideCurrents Through Single GABA and Glycine Receptor-Channels Can Be RecordedChloride Currents Through Inhibitory GABAA and Glycine Receptor-Channels Normally Inhibit the Postsynaptic CellIonotropic Glutamate, GABA, and Glycine Receptors Are Transmembrane Proteins Encoded by Two Distinct Gene FamiliesIonotropic GABAA and Glycine Receptors Are Homologous to Nicotinic ACh ReceptorsSome Synaptic Actions Depend on Other Types of Ionotropic Receptors in the Central Nervous SystemExcitatory and Inhibitory Synaptic Actions Are Integrated by the Cell into a Single OutputSynaptic Inputs Are Integrated to Fire an Action Potential at the Axon Initial SegmentDendrites Are Electrically Excitable Structures That Can Fire Action PotentialsSynapses on a Central Neuron Are Grouped According to Physiological FunctionAn Overall View