RT Book, Section A1 Zembutsu, Hitoshi A1 Nakamura, Yusuke A2 Murray, Michael F. A2 Babyatsky, Mark W. A2 Giovanni, Monica A. A2 Alkuraya, Fowzan S. A2 Stewart, Douglas R. SR Print(0) ID 1102698622 T1 Tamoxifen Pharmacogenetics T2 Clinical Genomics: Practical Applications in Adult Patient Care YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071622448 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1102698622 RD 2024/04/18 AB Drug summary:Tamoxifen is widely used antiestrogen therapy for pre- and postmenopausal women with metastatic breast cancer, for prevention of recurrence as adjuvant therapy, and for women with a high risk of developing breast cancer as chemoprevention.Five years of adjuvant tamoxifen safely reduces 15-year risks of breast cancer recurrence.The most frequent adverse events by tamoxifen treatment is hot flash (>60%).