RT Book, Section
A1 Joy, Tisha R.
A1 Hegele, Robert A.
A2 Murray, Michael F.
A2 Babyatsky, Mark W.
A2 Giovanni, Monica A.
A2 Alkuraya, Fowzan S.
A2 Stewart, Douglas R.
SR Print(0)
ID 1102698790
T1 Metabolic Syndrome
T2 Clinical Genomics: Practical Applications in Adult Patient Care
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 9780071622448
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1102698790
RD 2024/04/19
AB Disease  summary:Metabolic  syndrome  (MetS)  is  a  complex  genetic  disorder,  involving  the  interaction  of  multiple  genetic  loci  with  environmental  factors.MetS  consists  of  three  of  the  five  following  criteria:  increased  waist  circumference  (Table  12-1);  triglyceride  (TG)  level  greater  than  or  equal  to  150  mg/dL  (1.7  mmol/L)  or  drug  treatment  for  elevated  TG;  high-density  lipoprotein-cholesterol  (HDL-C)  less  than  40  mg/dL  (1  mmol/L)  in  males  or  less  than  50  mg/dL  (1.3  mmol/L)  in  females  or  drug  treatment  for  reduced  HDL-C  level;  systolic  blood  pressure  (SBP)  greater  than  or  equal  to  130  mm  Hg  and/or  diastolic  blood  pressure  (DBP)  greater  than  or  equal  to  85  mm  Hg  or  antihypertensive  drug  treatment  in  a  patient  with  a  history  of  elevated  blood  pressure  (BP);  fasting  glucose  greater  than  or  equal  to  100  mg/dL  (5.6  mmol/L)  or  drug  treatment  for  elevated  glucose.Individuals  with  MetS  have  a  twofold  increased  risk  for  cardiovascular  disease  (CVD)  and  fivefold  increased  risk  for  type  2  diabetes  (DM2)  compared  to  individuals  without  MetS.