RT Book, Section
A1 Szarek, Eva
A1 Xekouki, Paraskevi
A1 Stratakis, Constantine A.
A2 Murray, Michael F.
A2 Babyatsky, Mark W.
A2 Giovanni, Monica A.
A2 Alkuraya, Fowzan S.
A2 Stewart, Douglas R.
SR Print(0)
ID 1102701635
T1 Pituitary Tumors and Syndromes
T2 Clinical Genomics: Practical Applications in Adult Patient Care
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 9780071622448
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1102701635
RD 2023/03/21
AB Disease  summary:Pituitary  tumors  are  typically  of  monoclonal  origin  (although  not  always);  they  are  benign,  often  slow-growing,  adenomas  of  the  sella  arising  sporadically  or  rarely  in  the  context  of  hereditary  genetic  syndromes  accounting  for  10%  to  15%  of  all  diagnosed  intracranial  neoplasms.  Their  true  incidence  is  difficult  to  determine,  as  they  are  often  asymptomatic.  They  can  be  effectively  managed,  as  they  are  rarely  malignant.  Small  pituitary  tumors  go  largely  undetected  and  are  often  only  documented  during  postmortem  studies;  over  20%  of  the  adult  population  may  have  a  pituitary  adenoma,  identified  incidentally  by  imaging  studies  (called  “incidentalomas”).  Significant  morbidity  occurs  due  to  the  pituitary  tumor’s  effect  on  hormone  secretion  and  compression  of  regional  structures.  Other  symptoms  include  those  from  mass  effects.