RT Book, Section A1 Daniel, Benjamin S. A1 Murrell, Dedee F. A2 Murray, Michael F. A2 Babyatsky, Mark W. A2 Giovanni, Monica A. A2 Alkuraya, Fowzan S. A2 Stewart, Douglas R. SR Print(0) ID 1102704238 T1 Epidermolysis Bullosa T2 Clinical Genomics: Practical Applications in Adult Patient Care YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071622448 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1102704238 RD 2024/03/28 AB Disease summary:Inherited epidermolysis bullosa (EB) is a heterogenous group of genodermatoses characterized by blisters and erosions after minimal trauma. There are four main types of EB, namely epidermolysis bullosa simplex (EBS), junctional epidermolysis bullosa (JEB), dystrophic epidermolysis bullosa (DEB), and mixed Kindler syndrome. Diagnosis is made by a combination of electron microscopy (EM) and immunofluorescence findings. Management consists of avoiding trauma and preventing complications. In lethal cases, supportive measures are instituted as well as providing emotional and financial support for families or carers.Hereditary basis:Autosomal recessive and autosomal dominantDifferential diagnosis:Bullous pemphigoid, pemphigus vulgaris, linear IgA disease, arthropod bites, bullous lupus erythematosus, epidermolysis bullosa acquisita